12/8/2023 0 Comments Hydrogen peroxide teeth whitening![]() ![]() Recommendations around teeth whitening may need to shift, the study suggested, adding that shorter exposure time to a teeth whitening agent, as well as lower CP concentration, can still provide the colour change that consumers desire while causing less damage to their teeth. Researchers noted that their study has some limitations, including not studying cellular recovery to see if any occurred after treatments, and studying the teeth in a lab setting as opposed to inside a person’s mouth. Researchers found that teeth whitening agents with both a high concentration of CP and a long exposure time - treatments with 35 per cent CP applied for four hours - produced “intense oxidative stress on both and pulp cells, associated with a severe reduction in cell viability,” the study stated. At this concentration, researchers found that if CP made it to the dental pulp layer, dental pulp cells did not survive. Some of the teeth whitening treatments and products for sale online can contain up to 35 per cent CP. However, at five per cent CP, there was much less cell damage itself deeper in the tooth, the study said, while higher percentages had a much bigger impact on the cells themselves. ![]() The enamel protein was even affected at a low CP concentration of just five per cent, experiencing a 50 per cent reduction in enamel protein at five per cent and 16 per cent CP. The enamel protein was also cut down by the teeth whitening process, with researchers suggesting that oxidative degradation created by the CP was to blame. Microscopic imaging showed that dental cells themselves had changed in shape after whitening treatment, with a greater change visible the higher the CP percentage of the teeth whitening agent used. To make the circumstances as close to a real mouth as possible, researchers kept the teeth in artificial saliva between treatments. To study the effects of teeth-whitening agents, researchers exposed 30 teeth - which were in a lab setting, not anyone’s mouth - to different levels of CP for around two weeks, while 30 other teeth served as a control. ![]() This raised the question of how it could penetrate from the enamel into the pulp, and what exactly it was doing to the teeth along the way. The study explained that CP breaks down into hydrogen peroxide and urea and the whitening effect is thought to be caused by the hydrogen peroxide breaking down larger molecules in the dentin into smaller molecules that have “lesser or non-absorbing optical properties.”īozec had studied the effect of hydrogen peroxide on teeth before in the context of root canals, and had found that it caused damage to collagen. Teeth have layers - the enamel layer is the outside, followed by the dentin and then the central “pulp” section. ![]() “Here, we wanted to further understand the impact on the enamel itself and deep inside the pulp.” “We have always been interested in the effect of peroxide-based tooth whitening on the tooth structure and its link to sensitivity,” Laurent Bozec, an associate professor in U of T's Faculty of Dentistry and lead author of the study, said in a press release. Irritated gums and teeth sensitivity has been noted before as side-effects of teeth whitening, but the effect on the deep inside of the teeth isn’t fully understood, researchers said. Treatments containing CP are some of the most common types of tooth-whitening agents used at home. This loss of enamel protein allows the carbide peroxide (CP) to penetrate deeper into the tooth, leading to an increase in the death of dental cells themselves - but lessening the percentage of CP in the product may lower the risk. Bad news for those aiming for the brightest smile - according to a new Canadian study, certain teeth-whitening agents may be more dangerous than previously thought, able to damage not just the surface enamel, but all the way to the centre of the tooth.Ī study led by researchers with the University of Toronto and published last month in Nature Scientific Reports looked at carbide peroxide tooth whitening treatments, and found that the recommended application of just 10 per cent carbide peroxide can reduce enamel protein content by up to 50 per cent. ![]()
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